Challenges in Endocrine Disruptor Toxicology and Risk Assessment Hardc

Challenges in Endocrine Disruptor Toxicology and Risk Assessment Hardc Description

Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology - including interactions with other hormone pathways - has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease.