Fibrinolytic and Antithrombotic Therapy Theory, Practice, and Management

Thrombotic disorders of the circulatory system represent the leading cause of morbidity motality and health care expenditure in the United States. Fibrinolytic and Antithrombotic Therapy provides a practical evidence-based approach to the management of thrombotic disorders for all clinicians involved in the care of patients with these disorders. It provides not only vital conceptual information on fibrinolytic and antithrombotic therapy but also the means to apply it to everyday decision making and patient care. Focusing on management guidelines and critical pathways the text stresses practicality and usability. It will be a valuable resource for the wide range of clinicians involved in the care of patients with these disorders including cardiologists emergency physicians primary care physicians haematologists neurologists intensivists pharmacists and nurse practitioners. The origins of mammalian blood coagulation can be traced back over 400 million years. Despite its long history it is only within the past century that this complex and pivotal teleologic system has begun to be understood. Most recently the intricacies of haemostasis and pathologic thrombosis have come to light leading the way toward new more effective and safer treatment modalities. The Second Edition of Fibrinolytic and Antithrombotic Therapy even more concise and clinically relevant than the First provides vital evidence-based information on management of patients with arterial and venous thrombotic disorders. Since the First Edition the text has been expanded to cover the evolving topics of atherothrombosis thrombocardiology haematologic/thrombophilic conditions and vascular medicine. It includes up-to-date guidelines for antithrombotic and fibrinolytic therapy and offers concise summaries of current standards of care. Chapters are dedicated to discussions of patient-specific therapeutics and to the importance of genomics proteomics and metabolomics in defining genotype-phenotype relationships while throughout the book coagulation inflammation and vascular medicine are newly examined as elements in an intricately-linked triad of biochemical and cellular based phenomenology.

Alternative names:

• ISBN Fibrinolytic and Antithrombotic Therapy ( Theory Practice and Management ) English